Cat No.
CEI-0457
Description
A diacylglycerol acyltransferase (DGAT) inhibitor. Shows inhibitory effect in rat liver microsomes (IC50 = 10.2 μM) and Raji cells (IC50 = 15.5 μM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
CAS No.
169181-28-6
Product_Overview
A diacylglycerol acyltransferase (DGAT) inhibitor
Targets
DGAT1
Chemical Name
N-[4-[[4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl]oxy]-2-hydroxy-6-methylbenzoyl]-L-alanine
M.Wt
266.33
Purity
>97% by HPLC
Appearance
White solid
Solubility
DMSO (10 mg/ml) or EtOH
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
