Cat No.
CEI-0463
Description
A potent, selective, reversible, and slow binding dipeptidyl peptidase IV inhibitor (IC50 = 14 nM). Displays>15,000 fold selectivity over DPP-II and a range of Proline-cleaving proteases. Displays anti-diabetic activity in vivo, improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, and augments insulin secretion and GLUT-2 levels.
Alias
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile Dihydrochloride
Synonyms
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile Dihydrochloride
CAS No.
247016-69-9
Product_Overview
A potent DPP IV Inhibitor,
Targets
DPP4
Chemical Name
6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbononitrile Dihydrochloride
M.Wt
544.43
Purity
>98% by HPLC
Appearance
White to off-white solid
Solubility
H?O (~50 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
