Cat No.
CEI-0155
Description
PD318088
CAS No.
391210-00-7
Targets
MEK1/2
M.Wt
561.09
Purity
>99%
Solubility
No
Storage
2 years at -20 centigrade
In vitro
PD318088 is a small-molecule inhibitor of MEK1/2, which is an analog of PD184352, suggesting it might have substantial anti-proliferative activity against cancer cells, although no functional study of PD318088 is currently available. PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
