Cat No.
CEI-1086
Description
AV-412 is an orally bioavailable dual kinase inhibitor with potential antineoplastic activity. It binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2).
Abbr
AV-412(EGFR, ERBB2)
Alias
ERBB, ERBB1, HER1, PIG61, Mena
Synonyms
ERBB, ERBB1, HER1, PIG61, Mena
CAS No.
451492-95-8
Product_Overview
Inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2)
Targets
EGFR, HER2
Chemical Name
N-(4-(3-chloro-4-fluorophenylamino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl)quinazolin-6-yl)acrylamide
M.Wt
507
Purity
> 95%
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Storage
-20 centigrade
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
