Cat No.
CEI-0599
Description
Cell-permeable. A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor (Ki = 400 nM). Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.
CAS No.
328968-36-1
Product_Overview
A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor
Targets
EP300, CREBBP
Chemical Name
(E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
M.Wt
503
Purity
>98% by TLC
Appearance
White solid
Solubility
DMSO
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and mositure
Usage
For Research Use Only! Not For Use in Humans.
