Cat No.
CEI-0475
Description
A potent and selective inhibitor of histone lysine N-methyltransferase EZH2 (Ki = 24 nM). It displays more than 500-fold selectivity against 15 other protein methyltransferases and has 50-fold selectivity against the closely related enzyme, EZH1.
CAS No.
1396772-26-1
Product_Overview
A potent EZH2 inhibitor
Targets
EZH2
Chemical Name
1-Cyclopentyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-(4-(morpholinomethyl)phenyl)-1H-indazole-4-carboxamide
M.Wt
475.6
Purity
>98% by HPLC
Appearance
White to off-white solid
Solubility
DMSO (10 mg/ml)
Storage
+4 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
