Cat No.
CEI-0484
Description
An indolocarbazole derivative with antineoplastic properties. Acts as a potent inhibitor of several tyrosine kinases including FLT3, JAK2, and TrkA with IC50 values of 3, 1, and <25 nM, respectively. It suppresses JAK2/STAT5 signaling and is effective against myeloproliferative disorders in vivo.
Alias
CEP-701; KT-5555; SPM-924
Synonyms
CEP-701; KT-5555; SPM-924
CAS No.
111358-88-4
Product_Overview
A PTK inhibitor
Targets
FLT3, JAK2, NTRK1
M.Wt
1009.17
Purity
>98%
Appearance
White solid
Solubility
DMSO or EtOH
Storage
-20 centigrade
Shipping Conditions
RT
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
