Cat No.
CEI-0362
Description
Alendronate
Alias
Fosamax
Synonyms
Fosamax
CAS No.
121268-17-5
Targets
farnesyl diphosphate synthase
M.Wt
326.13
Purity
>99%
Solubility
DMSO
Storage
2 years at -20centigrade Powder
In vitro
Candesartan binds with high specificity to the angiotensin II AT1 receptors in CHO-AT1 cells with K?1 of 0.001 min?1. Candesartan does not affect cell viability or proliferation but increases the expression of VEGF and interleukin-8 in the cultured medium of KU-19-19 cells. Candesartan (0.1 nM) could reduce the maximal contractile response to angiostensin II by approximately 50%.
