Cat No.
CEI-0705
Description
Cell-permeable. A potent and selective γ-secretase inhibitor (IC50 = 17 nM) .Displays> 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides (IC50 values are 48 and 67 nM respectively in human neuroblastoma cells).
CAS No.
292632-98-5
Product_Overview
A γ-secretase inhibitor
Targets
gamma-secretase
Chemical Name
5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-( 2R)-benzylhexanoyl)-L-leucyl-L-phenylalaninamide
M.Wt
461.55
Purity
>98% by TLC
Appearance
White solid
Solubility
DMSO (100 mM)
Storage
2-8 centigrade
Shipping Conditions
RT
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
