Cat No.
CEI-0095
Description
SB 415286
CAS No.
264218-23-7
Targets
GSK3-alpha
M.Wt
359.72
Purity
>99%
Solubility
No
Storage
2 years at -20 centigrade
In vitro
SB 415286 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI3-kinase pathway activity in a concentration-dependent manner, which is correlated with inhibition of GSK-3 activity and modulation of GSK-3 substrates tau and beta-catenin.
