Cat No.
CEI-0503
Description
SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50 = 0.25 μM) and HDAC3 (IC50 = 0.30 μM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines.
Alias
Suberohydroxamic acid; suberic bis-hydroxamic acid; N, N-dihydroxyoctanediamide
Synonyms
Suberohydroxamic acid; suberic bis-hydroxamic acid; N,N-dihydroxyoctanediamide
CAS No.
38937-66-5
Product_Overview
A potent HDAC inhibitor
Targets
HDAC
M.Wt
328.41
Purity
>98% by HPLC
Appearance
Light brown solid
Solubility
DMSO (~100 mM) or EtOH (~ 20 mM) or 1 eq. HCl (50 mM)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from light and air
Usage
For Research Use Only! Not For Use in Humans.
