Cat No.
CEI-0499
Description
(LBH589) is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumour cell proliferation in vitro. The IC?? values of HDAC isozymes HDAC1-IP Ac-H4, HDAC8, MALunselective, B61HDAC1 and B12HDAC6 are 0.23±0.06, 283±29, 75±4, 47±5 and 89±12 nM, respectively. And to A2780 proliferation, IC?? value is 4.6±1.8 nM.
Alias
LBH589, LBN-589, NVP-LBH590
Synonyms
LBH589, LBN-589, NVP-LBH590
CAS No.
404950-80-7
Product_Overview
A HDAC inhibitor
Targets
HDAC
M.Wt
371.27
Purity
>98% by HPLC
Appearance
White solid
Solubility
DMSO (~100 mM) or EtOH (~ 100 mM)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
