Cat No.
CEI-0498
Description
Potent inhibitor of yeast NAD?dependent histone deacetylase Sir2p (IC50 = 60 μM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.
CAS No.
1384339
Product_Overview
A HDAC inhibitor
Targets
HDAC
Chemical Name
1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
M.Wt
513.49
Purity
>95% by HPLC
Appearance
Lyophilized solid
Solubility
DMSO (200 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
