Cat No.
CEI-0495
Description
A potent, cell permeable inhibitor of histone deacetylase (IC?? = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC?? = 50 – 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also prevents H-ras-induced invasive phenotype of MCF-10A cells possibly by down regulating MMP-2 in a reversible manner.
CAS No.
183506-66-3
Product_Overview
A HDAC inhibitor
Targets
HDAC
Chemical Name
cyclo-L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl]Suberoylanilide hydroxamic acid
M.Wt
415.2
Purity
>98% by ?1V-NMR
Appearance
Gray solid
Solubility
H?O (>5 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
