Cat No.
CEI-0581
Description
Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC?? = 180 nM)
Alias
Methylthiohydantoin-DL-tryptophan; Nec-1
Synonyms
Methylthiohydantoin-DL-tryptophan; Nec-1
CAS No.
4311-88-0
Product_Overview
A necroptosis inhibitor
Targets
Necroptosis
Chemical Name
5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
M.Wt
333.34
Purity
>97% by elemental analysis
Appearance
White solid
Solubility
Water
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from light and mositure
Usage
For Research Use Only! Not For Use in Humans.