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Cat No.
CEI-0541
Description
Cell-permeable. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd >97 nM). In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with K? values of 2 and 50 μM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices.
Alias
N-(3-(Aminomethyl)benzyl)acetamidine . 2HCl
Synonyms
N-(3-(Aminomethyl)benzyl)acetamidine . 2HCl
CAS No.
214358-33-5
Product_Overview
A highly selective iNOS inhibitor
Targets
NOS2
M.Wt
523.88
Purity
>95%
Appearance
White solid
Solubility
Acetic Acid (5%) or 10 mM HCl
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
