Cat No.
DIA-293
Description
Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. CBS uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.
Abbr
CBS, Recombinant
Alias
CBS
Enzyme Commission Number
EC 4.2.1.22
Appearance
Lyophilized powder
Molecular Mass
56 KD
Purification
>90% (by SDS-PAGE)
pH Stability
7.4-8.5
Isoelectric point
6.49
Applications
This protein can be used for producing Hcy in vitro diagnosis Kit .
Synonyms
Cystathionine-β-synthase; CBS; EC 4.2.1.22; 9023-99-8