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Cat No.
DIA-143
Description
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is a cytosolic enzyme that catalyzes the chemical reaction:D-glucose 6-phosphate + NADP+ ? 6-phospho-D-glucono-1,5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH).
Abbr
G6PDH (Bacillus sp.)
Alias
G6PDH; GPD; G6PD1; G6PD
Species
Bacillus sp.
Form
Freeze dried powder
Enzyme Commission Number
EC 1.1.1.49
Bio-activity
> 200 U/mg
CAS No.
9001-40-5
Appearance
White/off white powder
Molecular Mass
104 kDa dalton (two subunits of approx. 55 kDa)
Applications
Useful for enzymatic determination of glucose or ATP when coupled with hexokinase
Gene Name
G6PD (Homo sapiens)
Synonyms
Glucose-6-phosphate dehydrogenase; G6PD; G6PDH; Glucose-6-phosphate dehydrogenase (NADP(+)); EC 1.1.1.49; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate dehydrogenase; GPD
GeneID
2539
mRNA Refseq
NM_000402
Protein Refseq
NP_000393
MIM
305900
UniProt ID
P11413
Chromosome Location
Xq28
Pathway
Glutathione metabolism; Pentose phosphate pathway; Metabolism of carbohydrates.
Function
glucose-6-phosphate dehydrogenase activity; oxidoreductase activity; binding.
