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Cat No.
DIA-294
Description
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2
Abbr
UO, Recombinant
Alias
UO
Enzyme Commission Number
EC 1.7.3.3
Bio-activity
About 10U/mg
Appearance
White powder, lyophilized
Molecular Mass
About 45kDa (SDS-PAGE detection)
Purification
>90% (SDS-PAGE test)
Unit Definition
One unit will convert 1μmol uric acid to oxidize per min at pH 8.5 and at 37°C.
Applications
Uricase cancatalyze the enzymatic oxidation of uric acid to allantoate rapidly, so it is used to detect the amount of uric acid in the serum and urine.
Synonyms
urate oxidase; uric acid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II
