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Cat No.
NATE-0110
Description
Catalase activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. It functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids. Catalase has also been used to study the role reactive oxygen species play in gene expression and apoptosis.
Abbr
CAT, Native (Murine)
Alias
Catalase; CAT
Source
murine liver
Species
Murine
Form
ammonium sulfate suspension
Enzyme Commission Number
EC 1.11.1.6
Bio-activity
> 500 units/mg protein
CAS No.
2593710
Molecular Mass
tetramer mol wt ~250 kDa
Unit Definition
One unit will decompose 1.0 μmole of H2O2 per min at pH 7.0 at 25°C, while the H2O2 conc. falls from 10.3 to 9.2 mM.
Optimum pH
~7.0
Stability
2-8°C
Gene Name
Cat catalase [Mus musculus]
Synonyms
EC 1.11.1.6; Catalase; catalase; equilase; caperase; optidase; catalase-peroxidase; CAT; H2O2:H2O2 oxidoreductase
GeneID
12359
mRNA Refseq
NM_009804
Protein Refseq
NP_033934
UniProt ID
P24270
Chromosome Location
2 E3; 2 54.43 cM
Pathway
Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Cellular responses to stress, organism-specific biosystem; FoxO signaling pathway, organism-specific biosystem
Function
NADP binding; aminoacylase activity; antioxidant activity
