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Cat No.
NATE-0197
Description
D-lactic dehydrogenase catalyzes the conversion of D-lactate into D-pyruvate while reducing NAD+ to NADH and H+.
Abbr
D-LDH, Native (Staphylococcus epidermidis)
Alias
D-LDH
Species
Staphylococcus epidermidis
Form
Lyophilized powder containing primarily dextran
Enzyme Commission Number
EC 1.1.1.28
Bio-activity
> 80 units/mg solid
CAS No.
9028-36-8
Unit Definition
One unit will reduce 1.0 μmole of pyruvate to D-lactate per min at pH 7.0 at 25°C.
Applications
D-Lactic Dehydrogenase can be used to generate inhibitors of angiotensin converting enzyme by catalyzing the production of the intermediate (R)-2-Hydroxy-4-phenylbutyric acid. D-Lactic dehydrogenase has been used in a study to assess mechanisms of active transport in isolated membrane vesicles. It has also been used in a study to investigate β-galactoside transport in bacterial membrane preparations.
Synonyms
EC 1.1.1.28, D-Lactic Dehydrogenase; 9028-36-8; lactic acid dehydrogenase; D-specific lactic dehydrogenase; D-(–)-lactate dehydrogenase (NAD); D-lactic acid dehydrogenase; D-lactic dehydrogenase; (R)-Lactate:NAD+ oxidoreductase; D?LDH
