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Cat No.
NATE-0254
Description
Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH.
Abbr
FDH, Native (Candida boidinii)
Alias
FDH; FDH I; FDH II; N-FDH
Species
Candida boidinii
Form
Type I, lyophilized powder; Type II, powder; Type III, clear brown liquid.
Enzyme Commission Number
EC 1.2.1.2
Bio-activity
Type I, 5.0-15.0 units/mg protein; Type II, 0.3-0.6 units/mg; Type III, ~50 U/mL.
CAS No.
9028-85-7
Unit Definition
One unit will oxidize 1.0 μmole of formate to CO2 per min in the presence of β-NAD at pH 7.6 at 37°C.
Applications
Formate Dehydrogenase (FDH) is used for diagnostics in large scale industrial pr ocesses. Its used in the production of an unnatural amino acid, tert-L-leucine, a component of some HIV protease and matrix metalloprotease inhibitors.
Synonyms
EC 1.2.1.2; 9028-85-7; formate-NAD oxidoreductase; FDH; FDH I; FDH II; N-FDH; formic hydrogen-lyase; formate hydrogenlyase; hydrogenlyase; NAD-linked formate dehydrogenase; NAD-dependent formate dehydrogenase; formate dehydrogenase (NAD); NAD-formate dehydrogenase; formate benzyl-viologen oxidoreductase; formic acid dehydrogenase
