Cat No.
NATE-0279
Description
Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles.
Abbr
GAPDH, Native (Chicken)
Alias
GAPDH
Source
Chicken muscle
Species
Chicken
Form
Lyophilized powder containing citrate buffer salts
Enzyme Commission Number
EC 1.2.1.12
Bio-activity
> 40 units/mg protein
CAS No.
9001-50-7
Unit Definition
One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25°C.
Gene Name
GAPDH glyceraldehyde-3-phosphate dehydrogenase [Gallus gallus]
Synonyms
EC 1.2.1.12; GAPDH; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); triosephosphate dehydrogenase; dehydrogenase, glyceraldehyde phosphate; phosphoglyceraldehyde dehydrogenase; 3-phosphoglyceraldehyde dehydrogenase; NAD+-dependent glyceraldehyde phosphate dehydrogenase; glyceraldehyde phosphate dehydrogenase (NAD+); glyceraldehyde-3-phosphate dehydrogenase (NAD+); NADH-glyceraldehyde phosphate dehydrogenase; glyceraldehyde-3-P-dehydrogenase; 9001-50-7
GeneID
374193
mRNA Refseq
NM_204305
Protein Refseq
NP_989636
UniProt ID
P00356
Chromosome Location
chromosome: 1
Pathway
Androgen Receptor Signaling Pathway, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem; Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, conserved biosystem
Function
NAD binding; identical protein binding; microtubule binding