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Cat No.
NATE-0313
Description
Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (aka glycerone phosphate, outdated) to sn-glycerol 3-phosphate. Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism. It is also a major contributor of electrons to the electron transport chain in the mitochondria.
Abbr
GPDH, Native (Rabbit)
Alias
GPDH
Source
Rabbit Muscle
Species
Rabbit
Form
Lyophilized
Enzyme Commission Number
EC 1.1.1.8
Bio-activity
> 15 U/mg solid
CAS No.
9075-65-4
Appearance
White to off-white powder
Molecular Mass
75200
Purification
Purified
Specificity
> 100 U/mg protein
Unit Definition
One unit will catalyze the reduction of one micromole of dihydroxyacetone phosphate to alpha-glycerophosphate per minute at pH 7.4 and 25°C.
Gene Name
Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) [Rattus norvegicus]
Synonyms
Glycerol-3-phosphate dehydrogenase; GPDH; alpha glycerol-3-phosphate dehydrogenase; alphaGPDH; glycerolphosphate dehydrogenase; EC 1.1.1.8; 9075-65-4; α-glycerol phosphate dehydrogenase (NAD); α-glycerophosphate dehydrogenase (NAD); glycerol 1-phosphate dehydrogenase; glycerol phosphate dehydrogenase (NAD); glycerophosphate dehydrogenase (NAD); hydroglycerophosphate dehydrogenase; L-α-glycerol phosphate dehydrogenase; L-α-glycerophosphate dehydrogenase; L-glycerol phosphate dehydrogenase; L-glycerophosphate dehydrogenase; NAD-α-glycerophosphate dehydrogenase; NAD-dependent glycerol phosphate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase; NAD-L-glycerol-3-phosphate dehydrogenase; NAD-linked glycerol 3-phosphate dehydrogenase; NADH-dihydroxyacetone phosphate reductase; glycerol-3-phosphate dehydrogenase (NAD)
GeneID
60666
mRNA Refseq
NM_022215
Protein Refseq
NP_071551
UniProt ID
O35077
Chromosome Location
chromosome: 7
Pathway
Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerophospholipid biosynthesis, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem
Function
NAD binding; glycerol-3-phosphate dehydrogenase [NAD+] activity; protein homodimerization activity
