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Cat No.
NATE-0365
Description
Ketoreductase reduces 4-chloroacetoacetate with NADPH as a cosubstrate.
Abbr
Ketoreductase, Recombinant
Source
E. coli
Enzyme Commission Number
EC 1.1.1.2
Bio-activity
> 0.2 units/mg； > 2.2 units/mg
CAS No.
9028-12-0
Unit Definition
1 U corresponds to the amount of enzyme which reduces 1 μmol 4-chloroacetoacetate per minute at pH 6.0 and 25°C (cosubstrate NADPH).
Package
Bottomless glass bottle. Contents are inside inserted fused cone.
Applications
Ketoreductases are used to study the stereospecificity of ketoreductase domains. They may be used to reduce precursors of α-chloroalcohols, which are synthetic intermediates for various pharmaceutical compounds. This product is recombinant and expressed in E. coli at > 2.2 units/mg.
Synonyms
Ketoreductase; EC 1.1.1.2; 9028-12-0
