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Cat No.
NATE-0440
Description
MAO's are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo-and xenobiotic amines. Substrate specificity differs for each isozyme.
Abbr
MAOA, Recombinant (Human)
Alias
MAO-A; MAOA
Source
Baculovirus infected BTI insect cells
Species
Human
Enzyme Commission Number
EC 1.4.3.4
CAS No.
231-791-2
Concentration
~2.5 mg per vial
Applications
Monoamine Oxidase A has been used in a study to assess abnormal behavior in a large kindred of males where a deficiency of enzymatic activity of monamine oxidase A was found. It has also been used in a study to investigate an ass ociation between smoking and the inhibition of MAOA.
Gene Name
MAOA monoamine oxidase A [Homo sapiens]
Synonyms
MAO-A; MAOA; EC 1.4.3.4; Monoamine Oxidase A; adrenalin oxidase; adrenaline oxidase; amine oxidase (ambiguous); amine oxidase (flavin-containing); amine:oxygen oxidoreductase (deaminating) (flavin-containing); epinephrine oxidase; monoamine:O2 oxidoreductase (deaminating); polyamine oxidase (ambiguous); serotonin deaminase; spermidine oxidase (ambiguous); spermine oxidase (ambiguous); tyraminase; tyramine oxidase
GeneID
4128
mRNA Refseq
NM_000240
Protein Refseq
NP_000231
UniProt ID
P21397
Chromosome Location
Xp11.4-p11.3
Pathway
Amine Oxidase reactions, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Biological oxidations, organism-specific biosystem
Function
flavin adenine dinucleotide binding; oxidoreductase activity; primary amine oxidase activity; serotonin binding
