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Cat No.
CEI-0703
Description
A potent, cell permeable and reversible inhibitor of β-secretase that corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 μM) in CHO cells stably transfected with wild-type APP751.
Product_Overview
A beta-secretase inhibitor
Targets
BACE1
M.Wt
588.56
Purity
>98% by HPLC
Appearance
White solid
Solubility
DMSO ( 25 mg/ml)
Storage
-20 centigrade
Shipping Conditions
RT
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
