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Cat No.
CEI-1019
Description
Novobiocin is an aminocoumarin antibiotic that is produced by Streptomyces niveus. Along with other aminocoumarin antibiotics, novobiocin is a very potent inhibitor of bacterial DNA gyrase. It works by targeting the GyrB subunit of the enzyme involved in energy transduction. Novo-TRX is Texas Red-labeled novobiocin, which can be used as a fluorescence probe in assays for screening DNA gyrase inhibitors.
Abbr
Novo-TRX(bacterial DNA gyrase)
CAS No.
1476-53-5 (Novobiocin, sodium salt)
IC50
0.6 μM
Targets
bacterial DNA gyrase
M.Wt
1357.5
Purity
>93.3%
Appearance
A red aqueous solution.
Formulation
Supplied as a 10 μM solution in anhydrous DMSO.
Storage
Store at or below -20 centigrade.
