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Cat No.
CEI-0436
Description
A synthetic peptide inhibitor that irreversibly inhibits caspase-3 and related protease/caspase activity and blocks apoptosis. DEVD is the specific recognition sequence found in poly (ADP-ribose) polymerase (PARP). The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-DEVD-FMK, Caspase-4 inhibitor (fluoromethylketone)
Synonyms
Z-DEVD-FMK, Caspase-4 inhibitor (fluoromethylketone)
Product_Overview
Caspase-3 inhibitor
Targets
Caspase-3
M.Wt
668.7
Purity
>98% by HPLC
Appearance
Pale yellow solid
Solubility
DMSO (~30 mg/ml) or H?O (~ 31 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
