Cat No.
CEI-0432
Description
A synthetic peptide that irreversibly inhibits activity of DEVD-dependent caspases (e.g., caspase-3 and caspase-7) and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-DEVD-FMK, Caspase-3 inhibitor (fluoromethylketone)
Synonyms
Z-DEVD-FMK, Caspase-3 inhibitor (fluoromethylketone)
Product_Overview
A caspase-3 inhibitor
Targets
caspase-3
M.Wt
462.56
Purity
>98% by HPLC
Appearance
Crystalline solid
Solubility
DMSO (~25 mg/ml) or Ethanol (~ 15 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.