Cat No.
CEI-0431
Description
A synthetic peptide that irreversibly inhibits activity of caspase-3 and related caspases and blocks apoptosis. The inhibitor is designed as a methyl ester to enhance cell permeability. The conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Biotin-DEVD-FMK, DEVD-FMK, Biotin-
Synonyms
Biotin-DEVD-FMK, DEVD-FMK, Biotin-
Product_Overview
A caspase-3 inhibitor
Targets
caspase-3
M.Wt
189.21
Purity
>99% by TLC
Appearance
White to off-white solid
Solubility
DMSO (~25 mg/ml) or EtOH (~25 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.